Wales Star Sam Costelow suffers a fresh injury blow.

Wales and Scarlets fly-half Sam Costelow has suffered a fresh setback weeks after seeing his Six Nations campaign wrecked by an ankle injury.

After missing the opening two rounds of the tournament, the 25-year-old started in the  10 jersey against Scotland in Cardiff and delivered a fine performance, pulling the strings as a revitalised Welsh side ran their opponents close.

However, he was forced off the pitch shortly before the hour mark at the Principality Stadium after injuring his ankle and, while he was not released from Steve Tandy's squad, missed Wales' remaining games against Ireland and Italy.

Now, Costelow has been ruled out of the Scarlets' clash with Leinster in the United Rugby Championship on Friday after hurting his ankle again.

Hookers Ryan Elias and Marnus van der Merwe are also unavailable as they go through concussion protocols.