Saracens Men will begin the defence of the Premiership title at home to Northampton Saints.
Allianz Park will welcome to the BT Sport cameras for the fixture on Saturday 19th October, kick-off 15H00.
Away matches against Leicester Tigers and Gloucester sandwich a north London-encounter with London Irish before a break in the domestic schedule for Europe at the start of November.
Mark McCall's side host Bristol Bears four days prior to Christmas Day and end the year on the road at Exeter Chiefs.
The first London derby against Harlequins takes place at Twickenham Stoop in January while the return match is the eagerly-anticipated head-to-head at Tottenham Hotspur Stadium (Saturday 28th March).
Sarries end the regular campaign on home soil against Bath.