Inside ball from Biggar and a good offload sees Wales up to the 22

McNicholl into the line puts a fend in

Short side to Halfpenny on the right

Back to Allan who clears downfield, Biggar finds McNicholl on the run back

Biggar gets the match underway for Wales

Anthems concluded and kickoff is just moments away

Jonathan Davies' message to George North as he steps into his No 13 role: "Trust your instincts, don't overthink it. Don't worry about what a centre does, just do what you have done well for the 90-plus other caps you've had."

The sides are out on the field, anthems to follow

Wales get the defence of their Six Nations Championship crown underway when they host Italy in the opening round. Wales swept all before them aside in last season's campaign on route to a Grand Slam, while Italy went winless without even picking up a single point in the table. When the sides met last year, Wales claimed a 26-15 away victory. Wales are also coming off a fourth placed finish at the 2019 Rugby World Cup, while Italy failed to make it out their pool.