Three new caps for Ireland as they get set for England
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Rory Best leads the team and is joined in the front row by Jack McGrath and Mike Ross. The second row sees Donnacha Ryan come in to partner Devin Toner while Josh van der Flier will make his international debut at openside in a backrow that includes CJ Stander and Jamie Heaslip.
The halfbacks are Conor Murray and Johnny Sexton with Robbie Henshaw shifting to outside centre and new cap Stuart McCloskey filling the No.12 shirt. Keith Earls returns to join Andrew Trimble and Rob Kearney in the back three.
The replacements include Richardt Strauss, Cian Healy, Nathan White, Ultan Dillane, Rhys Ruddock, Eoin Reddan, Ian Madigan and Simon Zebo.
The halfbacks are Conor Murray and Johnny Sexton with Robbie Henshaw shifting to outside centre and new cap Stuart McCloskey filling the No.12 shirt. Keith Earls returns to join Andrew Trimble and Rob Kearney in the back three.
The replacements include Richardt Strauss, Cian Healy, Nathan White, Ultan Dillane, Rhys Ruddock, Eoin Reddan, Ian Madigan and Simon Zebo.