Edinburgh have won their last three away games in the Champions Cup, their best-ever streak, and as many victories as they had managed in their previous 18 games on the road.
Racing have won 12 of their last 13 home games in the Champions Cup, only losing to fellow French side Toulouse in the 2018/19 quarter-finals.
Racing are looking to reach the quarter-finals of the Champions Cup for the fourth consecutive season, Leinster are the only other side able to match that feat this season.
This will be the fifth Champions Cup meeting between Racing and Edinburgh, the Scottish side won both their pool stage meetings in 2011/12 before Racing 92 returned the favour in both of their meetings in 2012/13
This weekend marks the first time in the history of tournament that a Round of 16 will be played as part of the knockout stage.